A gas tanker heading for Lagos exploded around the Sagamu interchange axis of the Lagos-Ibadan highway.
Three occupants, including the driver, sustained injuries and were rushed to a hospital for treatment.
Ogun Sector Commander of the Federal Road Safety Corps (FRSC), Ahmed Umar, confirmed the incident to newsmen.
According to him, FRSC operatives from Mowe and Sagamu had been urgently deployed to the scene of the fire outbreak.
Umar added that men of the Ogun State Fire Services were contacted as they helped in putting out the raging inferno.