Risk of all-cause death higher in people vaccinated with COVID vaccines–study

One and two doses of the COVID-19 vaccines were linked to an increase in all-cause mortality in a new peer-reviewed study that analyzed data from the Italian National Healthcare System.

Based on their analysis, a team of Italian researchers verified what they called “the real impact of the vaccination campaign” by comparing the risk of all-cause death among vaccinated and unvaccinated residents of the Italian province of Pescara.

In their multivariate analysis, the researchers found the risk of all-cause death to be higher for those vaccinated with one or two doses of the COVID-19 vaccine compared to the unvaccinated.

Those who received three or four doses had roughly the same risk of all-cause death as the unvaccinated, they said, in contrast with prior research done in the same region suggesting those with three or four doses had a lower risk of all-cause death.

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“We also found a slight but statistically significant loss of life expectancy for those vaccinated with 2 or 3/4 doses,” they said in the report, which they published June 30 in Microorganisms.

Dr. Peter McCullough told The Defender, “These findings call for an immediate halt of COVID-19 vaccination across the globe and a thorough investigation of what went wrong during the COVID-19 vaccine campaign.”

McCullough wrote on Substack that the paper’s main point is that “COVID-19 vaccination did not ‘save lives’ as so many in Washington have proclaimed without evidence.”

Alberto Donzelli, one of the Italian study’s authors, told The Defender the study is “an important advance” because it looks at all-cause mortality broken down by vaccination status, and accounts for confounding variables that may have affected earlier reports on COVID-19 vaccination and all-cause mortality.

McCullough also told The Defender the study’s findings are “cohesive” with those of a recent German study — currently available as a preprint —  which found COVID-19 vaccination was linked to increased all-cause death in 16 German states.

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For their study, Donzelli and his co-authors used the same data analyzed by other researchers in an earlier Italian study on COVID-19 vaccine effectiveness.

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The earlier study — which followed up with people two years after the start of the COVID-19 vaccination campaign — found that those who received one or two doses had a significantly higher risk of all-cause death, while those who received three or more vaccine doses had a lower risk of death.

However, these results were likely distorted due to “immortal time bias,” Donzelli and his co-authors said.

“The results are startling,” wrote McCullough. “COVID-19 specific deaths were not reduced with vaccination, however there was a U-shaped trend of note when COVID-19 deaths were adjusted per 1000 population: unvaccinated 1.98/1000, one dose 0.27/1000, two doses 1.08/1000, and 3/4 doses 3.5/1000.”

Additionally, Donzelli and his co-authors in their multivariate analysis found that those who received one dose of the COVID-19 vaccine had a hazard risk ratio — which is a statistical estimate of risk — of 2.4 for all-cause mortality, meaning they were much more likely to die compared to the unvaccinated.

“Those vaccinated with two doses showed an almost double hazard ratio of death: 1.98,” Donzelli pointed out.

These numbers are significantly worse than what was reported in the original study that hadn’t been corrected for the immortal time bias, he said. Correcting for that bias changed the results for those who were vaccinated with three or more doses, too.