Boston researchers create ‘more lethal’ strain of COVID-19

A team of 14 scientists at Boston University’s National Emerging Infectious Diseases Laboratories (NEIDL) developed a new strain of COVID-19 that killed 80% of the mice infected with the virus in a laboratory setting, according to a preprint study published Oct. 14.

Following the announcement, numerous news stories about the study’s results focused on the fatality rate observed in the laboratory mice used in the study.

However, behind the headlines, some scientists and others raised concerns about the nature of the research and the fact that it was partially funded by the National Institute of Allergy and Infectious Diseases (NIAID), headed by Dr. Anthony Fauci.

The research was conducted using what some scientists called “gain-of-function” research, raising concerns that this type of research — which some theorize led to the creation and escape of the original Wuhan strain of COVID-19 — is still being done, despite concerns that it could lead to more lab escapes and more pandemics.

Gain of function refers to the “manipulation of pathogens to make them more dangerous,” in the hope of “getting ahead of a future outbreak.”

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Commenting on the researchers’ announcement, Robert F. Kennedy, Jr., Children’s Health Defense chairman of the board and chief legal counsel, remarked on the potential danger of such research — and its federal funding:

“What could be more insane than Anthony Fauci funding more of his gain of function experiments to soup up coronavirus lethality in the middle of a pandemic caused by a juiced-up coronavirus that has killed millions?

Rachel Lapal Cavallario, Boston University’s associate vice president for public relations and social media, told the media the research conducted was not gain-of-function research and that, “In fact, this research made the virus [replication] less dangerous.”

However, others disputed that claim.

Sen. Roger Marshall (R-Kan.), a doctor, said the research involved “lethal gain of function virus research” that creates the “potential to kill more people than any singular nuclear weapon.”

“Viruses have managed to escape even the most secure labs,” Marshall said, adding that this type of “research must stop immediately while the risks and benefits can be investigated.”

“The research was reviewed and approved by the Institutional Biosafety Committee (IBC), which consists of scientists as well as local community members. The Boston Public Health Commission also approved the research.

“Furthermore, this research mirrors and reinforces the findings of other, similar research performed by other organizations, including the FDA. Ultimately, this research will provide a public benefit by leading to better, targeted therapeutic interventions to help fight against future pandemics.”

However, this particular research took place under BSL-3 precautions, although according to STAT, “There is no evidence the work … was conducted improperly or unsafely,” noting that an internal biosafety review committee and the Boston Public Health Commission approved the work.

University of Illinois international law professor Francis Boyle, J.D., Ph.D., said the dangers of BSL-4 facilities have long been known, which is why he participated in efforts to stop the construction of the NEIDL facility.

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Boyle said the federal government “doesn’t rein in or prosecute” scientists working on such projects, “because the federal government is paying for this type of Nazi biowarfare death science dirty work.”

Such research, and the facilities in which it is performed, also pose a risk to surrounding communities and the world at large, Boyle said, suggesting a Wuhan-like leak could occur at any similar facility in the U.S.:

Following the publication of the preprint study — and the controversy that ensued — the NIAID appeared to distance itself from the research. According to STAT, “The research team did not clear the work” with the NIAID, leading the agency to look “for some answers as to why it first learned of the work through media reports.”

According to the MetroUK, “The scientists also infected human cells with the hybrid variant and found it was five times more infectious than Omicron.”

In the preprint, the researchers wrote: “We generated chimeric recombinant SARS-CoV-2 encoding the S gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate and compared this virus with the naturally circulating Omicron variant.